Cardiovascular regenerative therapeutics via synthetic paracrine factor modified mRNA

The heart has a limited capacity for regeneration following injury. Recent strategies to promote heart regeneration have largely focused on autologous and allogeneic cell-based therapy, where the transplanted cells have been suggested to secrete unknown paracrine factors that are envisioned to promo...

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Bibliographic Details
Main Authors: Kathy O. Lui, Lior Zangi, Kenneth R. Chien
Format: Article
Language:English
Published: Elsevier 2014-11-01
Series:Stem Cell Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1873506114000804