Hepatitis C virus-induced cytoplasmic organelles use the nuclear transport machinery to establish an environment conducive to virus replication.

Hepatitis C virus-induced cytoplasmic organelles use the nuclear transport machinery to establish an environment conducive to virus replication.

Hepatitis C virus (HCV) infection induces formation of a membranous web structure in the host cell cytoplasm where the viral genome replicates and virions assemble. The membranous web is thought to concentrate viral components and hide viral RNA from pattern recognition receptors. We have uncovered...

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Bibliographic Details
Main Authors: Christopher J Neufeldt, Michael A Joyce, Aviad Levin, Rineke H Steenbergen, Daniel Pang, Justin Shields, D Lorne J Tyrrell, Richard W Wozniak
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-10-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24204278/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/24204278/?tool=EBI

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