Persistent DNA Double-Strand Breaks After Repeated Diagnostic CT Scans in Breast Epithelial Cells and Lymphocytes

Persistent DNA Double-Strand Breaks After Repeated Diagnostic CT Scans in Breast Epithelial Cells and Lymphocytes

DNA double-strand break (DSB) induction and repair have been widely studied in radiation therapy (RT); however little is known about the impact of very low exposures from repeated computed tomography (CT) scans for the efficiency of repair. In our current study, DSB repair and kinetics were investig...

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Bibliographic Details
Main Authors: Natalia V. Bogdanova, Nina Jguburia, Dhanya Ramachandran, Nora Nischik, Katharina Stemwedel, Georg Stamm, Thomas Werncke, Frank Wacker, Thilo Dörk, Hans Christiansen
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-04-01
Series:Frontiers in Oncology
Subjects:
computed tomography
low-dose x-ray exposure
DNA double-strand breaks
persistent repair foci
radiation-induced long-term response
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.634389/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.634389/full

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