The natural killer cell response to West Nile virus in young and old individuals with or without a prior history of infection.

West Nile virus (WNV) typically leads to asymptomatic infection but can cause severe neuroinvasive disease or death, particularly in the elderly. Innate NK cells play a critical role in antiviral defenses, yet their role in human WNV infection is poorly defined. Here we demonstrate that NK cells mou...

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Bibliographic Details
Main Authors: Yi Yao, Dara M Strauss-Albee, Julian Q Zhou, Anna Malawista, Melissa N Garcia, Kristy O Murray, Catherine A Blish, Ruth R Montgomery
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5325267?pdf=render