Profiling the dead: generating microsatellite data from fossil bones of extinct megafauna--protocols, problems, and prospects.

We present the first set of microsatellite markers developed exclusively for an extinct taxon. Microsatellite data have been analysed in thousands of genetic studies on extant species but the technology can be problematic when applied to low copy number (LCN) DNA. It is therefore rarely used on subs...

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Bibliographic Details
Main Authors: Morten E Allentoft, Charlotte Oskam, Jayne Houston, Marie L Hale, M Thomas P Gilbert, Morten Rasmussen, Peter Spencer, Christopher Jacomb, Eske Willerslev, Richard N Holdaway, Michael Bunce
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21304955/?tool=EBI