Liver disease with unknown etiology – have you ruled out alpha-1 antitrypsin deficiency?

Although a less well-known consequence of alpha-1 antitrypsin deficiency (AATD) liver disease is the second leading cause of death among patients with the condition. The alpha-1 antitrypsin (AAT) protein is produced by hepatocytes within the liver, which retain pathological variants of AAT instead o...

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Bibliographic Details
Main Authors: Dhiren Patel, Jeffrey Teckman
Format: Article
Language:English
Published: SAGE Publishing 2021-06-01
Series:Therapeutic Advances in Chronic Disease
Online Access:https://doi.org/10.1177/2040622321995684