Identifying Promiscuous Compounds with Activity against Different Target Classes

Compounds with multitarget activity are of high interest for polypharmacological drug discovery. Such promiscuous compounds might be active against closely related target proteins from the same family or against distantly related or unrelated targets. Compounds with activity against distinct targets...

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Bibliographic Details
Main Authors: Christian Feldmann, Filip Miljković, Dimitar Yonchev, Jürgen Bajorath
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/22/4185