Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration

Connexin 43 and Sonic Hedgehog Pathway Interplay in Glioblastoma Cell Proliferation and Migration

Glioblastoma (GBM) represents the most common primary brain tumor within the adult population. Current therapeutic options are still limited by high rate of recurrences and signalling axes that promote GBM aggressiveness. The contribution of gap junctions (GJs) to tumor growth and progression has be...

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Bibliographic Details
Main Authors: Filippo Torrisi, Cristiana Alberghina, Debora Lo Furno, Agata Zappalà, Samuel Valable, Giovanni Li Volti, Daniele Tibullo, Nunzio Vicario, Rosalba Parenti
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Biology
Subjects:
GBM
connexin
gap junction
smoothened
GLI1
Online Access:https://www.mdpi.com/2079-7737/10/8/767

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https://www.mdpi.com/2079-7737/10/8/767

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