Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study

Epigenome-Wide Association Study of Soluble Tumor Necrosis Factor Receptor 2 Levels in the Framingham Heart Study

Background: Transmembrane tumor necrosis factor (TNF) receptors are involved in inflammatory, apoptotic, and proliferative processes. In the bloodstream, soluble TNF receptor II (sTNFR2) can modify the inflammatory response of immune cells and is predictive of cardiovascular disease risk. We hypothe...

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Bibliographic Details
Main Authors: Michael M. Mendelson, Roby Johannes, Chunyu Liu, Tianxiao Huan, Chen Yao, Xiao Miao, Joanne M. Murabito, Josée Dupuis, Daniel Levy, Emelia J. Benjamin, Honghuang Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Pharmacology
Subjects:
DNA methylation
TNFR2 levels
inflammation
association studies
epigenome
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2018.00207/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2018.00207/full

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