Comparative Study of the Temperature Sensitive, Cold Adapted and Attenuated Mutations Present in the Master Donor Viruses of the Two Commercial Human Live Attenuated Influenza Vaccines

Influenza viruses cause annual, seasonal infection across the globe. Vaccination represents the most effective strategy to prevent such infections and/or to reduce viral disease. Two major types of influenza vaccines are approved for human use: inactivated influenza vaccines (IIVs) and live attenuat...

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Bibliographic Details
Main Authors: Laura Rodriguez, Pilar Blanco-Lobo, Emma C. Reilly, Tatsuya Maehigashi, Aitor Nogales, Andrew Smith, David J. Topham, Stephen Dewhurst, Baek Kim, Luis Martínez-Sobrido
Format: Article
Language:English
Published: MDPI AG 2019-10-01
Series:Viruses
Subjects:
Online Access:https://www.mdpi.com/1999-4915/11/10/928