Down-regulated GATA-1 up-regulates interferon regulatory factor 3 in lung adenocarcinoma

Abstract Interferon regulatory factor 3 (IRF-3) is widely known for its prompt response against viral infection by activating the interferon system. We previously reported that E2F1, Sp1 and Sp3 regulated transcriptional activity of IRF-3. Recently, different expression patterns of IRF-3 were found...

Full description

Bibliographic Details
Main Authors: Lu-Lu Wang, Zheng-Sen Chen, Wen-Di Zhou, Jin Shu, Xiao-Hua Wang, Rui Jin, Li-Li Zhuang, Mir Alireza Hoda, Hao Zhang, Guo-Ping Zhou
Format: Article
Language:English
Published: Nature Publishing Group 2017-05-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-02700-5