State-of-the-art automated patch clamp devices: Heat activation, action potentials and high throughput in ion channel screening
Ion channels are essential in a wide range of cellular functions and their malfunction underlies many disease states making them important targets in drug discovery. Diverse automated patch clamp systems with high-throughput capabilities are available for drug screening, but there are limitations in...
Main Authors: | Sonja eStoelzle, Alison eObergrussberger, Andrea eBruggemann, Claudia eHaarmann, Michael eGeorge, Ralf Franz Kettenhofen, Niels eFertig |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2011-11-01
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Series: | Frontiers in Pharmacology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00076/full |
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