Fronto-striatal structures related with model-based control as an endophenotype for obsessive–compulsive disorder

Abstract Recent theories suggest a shift from model-based goal-directed to model-free habitual decision-making in obsessive–compulsive disorder (OCD). However, it is yet unclear, whether this shift in the decision process is heritable. We investigated 32 patients with OCD, 27 unaffected siblings (SI...

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Bibliographic Details
Main Authors: Meltem I. Kasal, Lutfullah Besiroglu, Nabi Zorlu, Nur Dikmeer, Aslıhan Bilge, Ercan Durmaz, Serap Polat, Fazil Gelal, Michael Rapp, Andreas Heinz, Miriam Sebold
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91179-2