A family with Milroy disease caused by the FLT4/VEGFR3 gene variant c.2774 T > A

A family with Milroy disease caused by the FLT4/VEGFR3 gene variant c.2774 T > A

Abstract Background Milroy disease (MD) is a rare, autosomal-dominant disorder. Variants in the Fms-related tyrosine kinase 4 (FLT4/VEGFR3) gene cause the symptoms of this disease. In this report, we investigated the variant in a large Chinese family with MD. Methods We conducted Sanger sequencing o...

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Bibliographic Details
Main Authors: Yu Sui, Yongping Lu, Meina Lin, Xiang Ni, Xinren Chen, Huan Li, Miao Jiang
Format: Article
Language:English
Published: BMC 2021-06-01
Series:BMC Medical Genomics
Subjects:
Milroy disease
FLT4/VEGFR3
Heterogeneity
Online Access:https://doi.org/10.1186/s12920-021-00997-w

Internet

https://doi.org/10.1186/s12920-021-00997-w

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