Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals.
Family studies of individual tissues have shown that gene expression traits are genetically heritable. Here, we investigate cis and trans components of heritability both within and across tissues by applying variance-components methods to 722 Icelanders from family cohorts, using identity-by-descent...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2011-02-01
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| Series: | PLoS Genetics |
| Online Access: | http://europepmc.org/articles/PMC3044684?pdf=render |