Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses

Differential Impact of Single-Dose Fe Ion and X-Ray Irradiation on Endothelial Cell Transcriptomic and Proteomic Responses

Background and Purpose: Radiotherapy is an essential tool for cancer treatment. In order to spare normal tissues and to reduce the risk of normal tissue complications, particle therapy is a method of choice. Although a large part of healthy tissues can be spared due to improved depth dose characteri...

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Bibliographic Details
Main Authors: Bjorn Baselet, Omid Azimzadeh, Nadine Erbeldinger, Mayur V. Bakshi, Till Dettmering, Ann Janssen, Svetlana Ktitareva, Donna J. Lowe, Arlette Michaux, Roel Quintens, Kenneth Raj, Marco Durante, Claudia Fournier, Mohammed A. Benotmane, Sarah Baatout, Pierre Sonveaux, Soile Tapio, An Aerts
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-09-01
Series:Frontiers in Pharmacology
Subjects:
irradiation
radiotherapy
X-rays
Fe ions
linear energy transfer
endothelial cells
Online Access:http://journal.frontiersin.org/article/10.3389/fphar.2017.00570/full

Internet

http://journal.frontiersin.org/article/10.3389/fphar.2017.00570/full

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