COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

COMBImage2: a parallel computational framework for higher-order drug combination analysis that includes automated plate design, matched filter based object counting and temporal data mining

Abstract Background Pharmacological treatment of complex diseases using more than two drugs is commonplace in the clinic due to better efficacy, decreased toxicity and reduced risk for developing resistance. However, many of these higher-order treatments have not undergone any detailed preceding in...

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Bibliographic Details
Main Authors: Efthymia Chantzi, Malin Jarvius, Mia Niklasson, Anna Segerman, Mats G. Gustafsson
Format: Article
Language:English
Published: BMC 2019-06-01
Series:BMC Bioinformatics
Subjects:
Label-free time-lapse video microscopy
Automated plate design
Higher-order drug combination analysis
Matched filter
Resampling
Data mining
Online Access:http://link.springer.com/article/10.1186/s12859-019-2908-0

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http://link.springer.com/article/10.1186/s12859-019-2908-0

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