Myeloid infection links epithelial and B cell tropisms of Murid Herpesvirus-4.

Gamma-herpesviruses persist in lymphocytes and cause disease by driving their proliferation. Lymphocyte infection is therefore a key pathogenetic event. Murid Herpesvirus-4 (MuHV-4) is a rhadinovirus that like the related Kaposi's Sarcoma-associated Herpesvirus persists in B cells in vivo yet i...

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Bibliographic Details
Main Authors: Bruno Frederico, Ricardo Milho, Janet S May, Laurent Gillet, Philip G Stevenson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-09-01
Series:PLoS Pathogens
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23028329/?tool=EBI