Time-dependent effects of localized inflammation on peripheral clock gene expression in rats.

Many aspects of the immune system, including circulating cytokine levels as well as counts and function of various immune cell types, present circadian rhythms. Notably, the mortality rate of animals subjected to high doses of lipopolysaccharide is dependent on the time of treatment. In addition, th...

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Bibliographic Details
Main Authors: Susan Westfall, Argel Aguilar-Valles, Valérie Mongrain, Giamal N Luheshi, Nicolas Cermakian
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3603876?pdf=render