Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation

Nucleus size and DNA accessibility are linked to the regulation of paraspeckle formation in cellular differentiation

Abstract Background Many long noncoding RNAs (lncRNAs) have been implicated in general and cell type-specific molecular regulation. Here, we asked what underlies the fundamental basis for the seemingly random appearance of nuclear lncRNA condensates in cells, and we sought compounds that can promote...

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Bibliographic Details
Main Authors: Markus Grosch, Sebastian Ittermann, Ejona Rusha, Tobias Greisle, Chaido Ori, Dong-Jiunn Jeffery Truong, Adam C. O’Neill, Anna Pertek, Gil Gregor Westmeyer, Micha Drukker
Format: Article
Language:English
Published: BMC 2020-04-01
Series:BMC Biology
Online Access:http://link.springer.com/article/10.1186/s12915-020-00770-y

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http://link.springer.com/article/10.1186/s12915-020-00770-y

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