Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine

Virus-like vaccines against HIV/SIV synergize with a subdominant antigen T cell vaccine

Abstract Background In non-human primates (NHPs) and humans, partial protection from HIV/SIV infection or suppression of replication is achievable by Env-binding antibodies and Gag-specific CD8+ T-cells targeting protective epitopes. Unfortunately, such T-cell responses are frequently dominated by r...

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Bibliographic Details
Main Authors: Melanie Schwerdtfeger, Anne-Marie Carola Andersson, Lasse Neukirch, Peter Johannes Holst
Format: Article
Language:English
Published: BMC 2019-05-01
Series:Journal of Translational Medicine
Subjects:
Adenoviral vectors
Human immunodeficiency virus
Virus-like particles
Virus-like vaccines
T-cells
Antibodies
Online Access:http://link.springer.com/article/10.1186/s12967-019-1924-1

Internet

http://link.springer.com/article/10.1186/s12967-019-1924-1

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