Matrine Mediates Inflammatory Response via Gut Microbiota in TNBS-Induced Murine Colitis

Matrine Mediates Inflammatory Response via Gut Microbiota in TNBS-Induced Murine Colitis

This study mainly investigated the effect of matrine on TNBS-induced intestinal inflammation in mice. TNBS treatment caused colonic injury and gut inflammation. Matrine (1, 5, and 10 mg/kg) treatment alleviated colonic injury and gut inflammation via reducing bleeding and diarrhea and downregulating...

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Bibliographic Details
Main Authors: Peiyuan Li, Jiajun Lei, Guangsheng Hu, Xuanmin Chen, Zhifeng Liu, Jing Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-02-01
Series:Frontiers in Physiology
Subjects:
matrine
inflammation
gut microbiota
colitis
mouse
Online Access:https://www.frontiersin.org/article/10.3389/fphys.2019.00028/full

Internet

https://www.frontiersin.org/article/10.3389/fphys.2019.00028/full

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