Essential role for Argonaute2 protein in mouse oogenesis

<p>Abstract</p> <p>Background</p> <p>Argonaute2 protein (Ago2) is a key component of RNA-induced gene silencing complex, which is crucial for microRNA-mediated repression of target genes. The function of Ago2 in the mouse oocyte and early embryonic development is less w...

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Bibliographic Details
Main Authors: Kaneda Masahiro, Tang Fuchou, O'Carroll Dónal, Lao Kaiqin, Surani M Azim
Format: Article
Language:English
Published: BMC 2009-08-01
Series:Epigenetics & Chromatin
Online Access:http://www.epigeneticsandchromatin.com/content/2/1/9