Non-Covalent BTK Inhibitors—The New BTKids on the Block for B-Cell Malignancies

The B-cell receptor signalling pathway plays a critical role in development of B-cell malignancies, and the central role of Bruton’s tyrosine kinase (BTK) activation in this pathway provides compelling rationale for BTK inhibition as a therapeutic strategy for these conditions. Covalent BTK inhibito...

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Bibliographic Details
Main Authors: Katharine L Lewis, Chan Y Cheah
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:https://www.mdpi.com/2075-4426/11/8/764