Calcium Sensing Receptor Regulating Smooth Muscle Cells Proliferation Through Initiating Cystathionine-Gamma-Lyase/Hydrogen Sulfide Pathway in Diabetic Rat

Aims: Hydrogen sulfide (H2S) inhibits the proliferation of vascular smooth muscle cells (VSMCs). However, how cystathionine-gamma-lyase (CSE), a major enzyme that produces H2S, is regulated remains unknown. Whether calcium-sensing receptor (CaSR) inhibits the proliferation of VSMCs by regulating the...

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Bibliographic Details
Main Authors: Xin Zhong, Yuwen Wang, Jichao Wu, Aili Sun, Fan Yang, Dan Zheng, Ting Li, Shiyun Dong, Yajun Zhao, Guangdong Yang, Changqing Xu, Dianjun Sun, Fanghao Lu, Weihua Zhang
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2015-03-01
Series:Cellular Physiology and Biochemistry
Subjects:
Online Access:http://www.karger.com/Article/FullText/373973