The Cardiotoxicity Induced by Arsenic Trioxide is Alleviated by Salvianolic Acid A via Maintaining Calcium Homeostasis and Inhibiting Endoplasmic Reticulum Stress

Arsenic trioxide (ATO) has been verified as a breakthrough with respect to the management of acute promyelocytic leukemia (APL) in recent decades but associated with some serious adverse phenomena, particularly cardiac functional abnormalities. Salvianolic acid A (Sal A) is a major effective compone...

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Bibliographic Details
Main Authors: Ruiying Wang, Jingyi Zhang, Shan Wang, Min Wang, Tianyuan Ye, Yuyang Du, Xueheng Xie, Jingxue Ye, Guibo Sun, Xiaobo Sun
Format: Article
Language:English
Published: MDPI AG 2019-02-01
Series:Molecules
Subjects:
Online Access:https://www.mdpi.com/1420-3049/24/3/543