Macrophages Inability to Mediate Adherent-Invasive <i>E. coli</i> Replication is Linked to Autophagy in Crohn’s Disease Patients

Macrophages Inability to Mediate Adherent-Invasive <i>E. coli</i> Replication is Linked to Autophagy in Crohn’s Disease Patients

The macrophages from Crohn&#8217;s Disease (CD) patients are defective to control the replication of CD-associated adherent-invasive <i>E. coli</i> (AIEC). We aimed to identify the host factors associated with AIEC replication focusing on polymorphisms related to autophagy. Periphera...

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Bibliographic Details
Main Authors: Anthony Buisson, Clara Douadi, Lemlih Ouchchane, Marion Goutte, Jean-Pierre Hugot, Anaëlle Dubois, Régine Minet-Quinard, Damien Bouvier, Gilles Bommelaer, Emilie Vazeille, Nicolas Barnich
Format: Article
Language:English
Published: MDPI AG 2019-11-01
Series:Cells
Subjects:
crohn’s disease
macrophages
adherent-invasive <i>e. coli</i>
<i>irgm</i>
<i>ulk-1</i>
autophagy
Online Access:https://www.mdpi.com/2073-4409/8/11/1394

Internet

https://www.mdpi.com/2073-4409/8/11/1394

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