Red Wine administration to Apolipoprotein E-deficient Mice reduces their Macrophage-derived Extracellular Matrix Atherogenic Properties

Red Wine administration to Apolipoprotein E-deficient Mice reduces their Macrophage-derived Extracellular Matrix Atherogenic Properties

Proteoglycans (PGs) from the arterial extracellular matrix (ECM) contribute to the trapping of LDL and oxidized LDL (Ox-LDL) in the arterial wall, a phenomenon called "lipoprotein retention". Moreover, we have shown that subsequent to their binding to the matrix, LDL and Ox-LDL are taken u...

Full description

Bibliographic Details
Main Authors: MARIELLE KAPLAN, MICHAEL AVIRAM
Format: Article
Language:English
Published: BMC 2004-01-01
Series:Biological Research
Subjects:
Antioxidants
atherosclerosis
extracellular matrix
macrophages
polyphenols
proteoglycans
red wine
Online Access:http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000200010

Internet

http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602004000200010

Similar Items