High Salt Intake Increases Blood Pressure in Normal Rats: Putative Role of 20-HETE and No Evidence on Changes in Renal Vascular Reactivity

Background/Aims. High salt (HS) intake may elevate blood pressure (BP), also in animals without genetic salt sensitivity. The development of salt-dependent hypertension could be mediated by endogenous vasoactive agents; here we examined the role of vasodilator epoxyeicosatrienoic acids (EETs) and va...

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Main Authors: A. Walkowska, M. Kuczeriszka, J. Sadowski, K.H. Olszyñski, L. Dobrowolski, L. Červenka, B.D. Hammock, E. Kompanowska-Jezierska
Format: Article
Language:English
Published: Karger Publishers 2015-05-01
Series:Kidney & Blood Pressure Research
Subjects:
Online Access:http://www.karger.com/Article/FullText/368508