An effective approach to detecting both small and large complexes from protein-protein interaction networks

Abstract Background Predicting protein complexes from protein-protein interaction (PPI) networks has been studied for decade. Various methods have been proposed to address some challenging issues of this problem, including overlapping clusters, high false positive/negative rates of PPI data and dive...

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Bibliographic Details
Main Authors: Bin Xu, Yang Wang, Zewei Wang, Jiaogen Zhou, Shuigeng Zhou, Jihong Guan
Format: Article
Language:English
Published: BMC 2017-10-01
Series:BMC Bioinformatics
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12859-017-1820-8