Chloroquine increases phosphorylation of AMPK and Akt in myotubes

Chloroquine increases phosphorylation of AMPK and Akt in myotubes

Aims: There are reports that ataxia telangiectasia mutated (ATM) can activate the AMP-activated protein kinase (AMPK) and also Akt, two kinases that play integral parts in cardioprotection and metabolic function. We hypothesized that chloroquine and resveratrol, both known ATM activators, would also...

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Bibliographic Details
Main Authors: Larry D. Spears, Andrew V. Tran, Charles Y. Qin, Supriya B. Hobbs, Cheryl A. Liang Burns, Nathaniel K. Royer, Zhihong Zhang, Lyle Ralston, Jonathan S. Fisher
Format: Article
Language:English
Published: Elsevier 2016-03-01
Series:Heliyon
Subjects:
Applied sciences
Therapeutics in cell biology
Animal metabolism
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016300275

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http://www.sciencedirect.com/science/article/pii/S2405844016300275

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