Bioluminescent Monitoring of NIS-Mediated I Ablative Effects in MCF-7 Xenografts

Optical imaging has made it possible to monitor response to anticancer therapies in tumor xenografts. The concept of treating breast cancers with 131 I is predicated on the expression of the Na + /I − symporter (NIS) in many tumors and uptake of I in some. The pattern of 131 I radioablative effects...

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Bibliographic Details
Main Authors: Malavika Ghosh, Sanjiv Sam Gambhir, Abhijit De, Kent Nowels, Michael Goris, Irene Wapnir
Format: Article
Language:English
Published: Hindawi - SAGE Publishing 2006-04-01
Series:Molecular Imaging
Online Access:https://doi.org/10.2310/7290.2006.00008