The Role of Nitroreductases in Resistance to Nitroimidazoles

Antimicrobial resistance is a major challenge facing modern medicine, with an estimated 700,000 people dying annually and a global cost in excess of $100 trillion. This has led to an increased need to develop new, effective treatments. This review focuses on nitroimidazoles, which have seen a resurg...

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Bibliographic Details
Main Authors: Carol Thomas, Christopher D. Gwenin
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biology
Subjects:
Online Access:https://www.mdpi.com/2079-7737/10/5/388