MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients

MTP -493G/T gene polymorphism is associated with steatosis in hepatitis C-infected patients

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The reduction of hepatic microsomal transfer protein (MTP) activity results in fatty liver, worsening hepatic steatosis and fibrosis in chronic hepatitis C (CHC). The G allele of the MTP gene promoter, -493G/T, has been associated with lower transcriptional activity than the T allele. We investigate...

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Bibliographic Details
Main Authors: E.R.F. Siqueira, C.P.M.S. Oliveira, M.L. Correa-Giannella, J.T. Stefano, A.M. Cavaleiro, M.A.H.Z. Fortes, M.T.C. Muniz, F.S. Silva, L.M.M.B. Pereira, F.J. Carrilho
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2012-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Hepatitis C
Steatosis
Fibrosis
Microsomal transfer protein
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100012&lng=en&tlng=en

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2012000100012&lng=en&tlng=en

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