Uptake and intracellular trafficking of superantigens in dendritic cells.

Uptake and intracellular trafficking of superantigens in dendritic cells.

Bacterial superantigens (SAgs) are exotoxins produced mainly by Staphylococcus aureus and Streptococcus pyogenes that can cause toxic shock syndrome (TSS). According to current paradigm, SAgs interact directly and simultaneously with T cell receptor (TCR) on the T cell and MHC class II (MHC-II) on t...

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Bibliographic Details
Main Authors: María B Ganem, Mauricio C De Marzi, María J Fernández-Lynch, Carolina Jancic, Mónica Vermeulen, Jorge Geffner, Roy A Mariuzza, Marisa M Fernández, Emilio L Malchiodi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3682983?pdf=render

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http://europepmc.org/articles/PMC3682983?pdf=render

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