Composition and applications of focus libraries to phenotypic assays

The wealth of bioactivity information now available on low-molecular weight compounds has enabled a paradigm shift in chemical biology and early phase drug discovery efforts. Traditionally chemical libraries have been most commonly employed in screening approaches where a bioassay is used to charact...

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Bibliographic Details
Main Authors: Anne Mai eWassermann, Luiz Miguel Camargo, Douglas S. Auld
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00164/full