Deficiency of iPLA2β Primes Immune Cells for Proinflammation: Potential Involvement in Age-Related Mesenteric Lymph Node Lymphoma

Proinflammation can predispose the body to autoimmunity and cancer. We have reported that iPLA2β−/− mice are susceptible to autoimmune hepatitis and colitis. Here we determined whether cytokine release by immune cells could be affected by iPLA2β deficiency alone or combined with CD95/FasL-antibody t...

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Bibliographic Details
Main Authors: Johannes Inhoffen, Sabine Tuma-Kellner, Beate Straub, Wolfgang Stremmel, Walee Chamulitrat
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:Cancers
Subjects:
Online Access:http://www.mdpi.com/2072-6694/7/4/0901