Host immunity increases Mycobacterium tuberculosis reliance on cytochrome bd oxidase.

In order to sustain a persistent infection, Mycobacterium tuberculosis (Mtb) must adapt to a changing environment that is shaped by the developing immune response. This necessity to adapt is evident in the flexibility of many aspects of Mtb metabolism, including a respiratory chain that consists of...

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Bibliographic Details
Main Authors: Yi Cai, Eleni Jaecklein, Jared S Mackenzie, Kadamba Papavinasasundaram, Andrew J Olive, Xinchun Chen, Adrie J C Steyn, Christopher M Sassetti
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-07-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1008911