Peripheral non-viral MIDGE vector-driven delivery of β-endorphin in inflammatory pain

<p>Abstract</p> <p>Background</p> <p>Leukocytes infiltrating inflamed tissue produce and release opioid peptides such as β-endorphin, which activate opioid receptors on peripheral terminals of sensory nerves resulting in analgesia. Gene therapy is an attractive strategy...

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Bibliographic Details
Main Authors: Busch Melanie, Labuz Dominika, Brack Alexander, Rittner Heike L, Mousa Shaaban A, Sitte Nicolle, Binder Waltraud, Schroff Matthias, Oswald Detlef, Machelska Halina, Wittig Burghardt, Schäfer Michael, Stein Christoph
Format: Article
Language:English
Published: SAGE Publishing 2009-12-01
Series:Molecular Pain
Online Access:http://www.molecularpain.com/content/5/1/72