Lentivirus-Mediated Oncogene Introduction into Mammary Cells In Vivo Induces Tumors

We recently reported the introduction of oncogene-expressing avian retroviruses into somatic mammary cells in mice susceptible to infection by transgenic expression of tva, encoding the receptor for subgroup A avian leukosis-sarcoma virus (ALSV). Because ALSV-based vectors poorly infect nondividing...

Full description

Bibliographic Details
Main Authors: Stefan K. Siwko, Wen Bu, Carolina Gutierrez, Brian Lewis, Martin Jechlinger, Brian Schaffhausen, Yi Li
Format: Article
Language:English
Published: Elsevier 2008-07-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558608800036