Impaired excitatory drive to spinal GABAergic neurons of neuropathic mice.

Impaired excitatory drive to spinal GABAergic neurons of neuropathic mice.

Adequate pain sensitivity requires a delicate balance between excitation and inhibition in the dorsal horn of the spinal cord. This balance is severely impaired in neuropathy leading to enhanced pain sensations (hyperalgesia). The underlying mechanisms remain elusive. Here we explored the hypothesis...

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Bibliographic Details
Main Authors: Jörg Leitner, Sören Westerholz, Bernhard Heinke, Liesbeth Forsthuber, Gabriele Wunderbaldinger, Tino Jäger, Doris Gruber-Schoffnegger, Katharina Braun, Jürgen Sandkühler
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3751881?pdf=render

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http://europepmc.org/articles/PMC3751881?pdf=render

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