Immunohistochemical analysis of PDK1, PHD3 and HIF-1α expression defines the hypoxic status of neuroblastoma tumors.

Neuroblastoma (NB) is the most common solid tumor during infancy and the first cause of death among the preschool age diseases. The availability of several NB genomic profiles improves the prognostic ability, but the outcome prediction for this pathology remains imperfect. We previously produced a n...

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Bibliographic Details
Main Authors: Marzia Ognibene, Davide Cangelosi, Martina Morini, Daniela Segalerba, Maria Carla Bosco, Angela Rita Sementa, Alessandra Eva, Luigi Varesio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5678880?pdf=render