The Interleukin-6 Gene Promoter Polymorphism -174 and Atherosclerotic Events in Overweight Transplanted Patients

Chronic inflammation plays a pivotal role in atherosclerosis. We hypothesized that combining overweight and a greater genetic capacity to produce IL-6 predicted by IL-6 gene promoter polymorphism at position -174 (G→C) may allow to identify individuals exhibiting higher IL-6 and C-reactive protein (...

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Bibliographic Details
Main Authors: Jamal Bamoulid, Cécile Courivaud, Marina Deschamps, Béatrice Gaugler, Pierre Tiberghien, Jean-Marc Chalopin, Philippe Saas, Didier Ducloux
Format: Article
Language:English
Published: Hindawi Limited 2011-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2011/803429