Priming as a strategy to overcome detrimental pH effects on cells for intervertebral disc regeneration
Disc disease is characterised by degeneration of the nucleus pulposus (NP), the central gelatinous tissue of the intervertebral disc (IVD). As degeneration progresses, the microenvironment of the IVD becomes more hostile (i.e. decrease in oxygen, glucose and pH), providing a significant challenge fo...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
AO Research Institute Davos
2021-02-01
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Series: | European Cells & Materials |
Subjects: | |
Online Access: | https://www.ecmjournal.org/papers/vol041/pdf/v041a11.pdf |