EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid.

During Caenorhabditis elegans vulval development, the anchor cell (AC) in the somatic gonad secretes an epidermal growth factor (EGF) to activate the EGF receptor (EGFR) signaling pathway in the adjacent vulval precursor cells (VPCs). The inductive AC signal specifies the vulval fates of the three p...

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Bibliographic Details
Main Authors: Amit Dutt, Stefano Canevascini, Erika Froehli-Hoier, Alex Hajnal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2004-11-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC519001?pdf=render