Convergent RANK- and c-Met-mediated signaling components predict survival of patients with prostate cancer: an interracial comparative study.

We reported (PLoS One 6 (12):e28670, 2011) that the activation of c-Met signaling in RANKL-overexpressing bone metastatic LNCaP cell and xenograft models increased expression of RANK, RANKL, c-Met, and phosphorylated c-Met, and mediated downstream signaling. We confirmed the significance of the RANK...

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Bibliographic Details
Main Authors: Peizhen Hu, Leland W K Chung, Dror Berel, Henry F Frierson, Hua Yang, Chunyan Liu, Ruoxiang Wang, Qinlong Li, Andre Rogatko, Haiyen E Zhau
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3774681?pdf=render