2-Aryl-6,8-dibromo-2,3-dihydroquinazolin-4(1H)-ones as substrates for the synthesis of 2,6,8-triarylquinazolin-4-ones

Direct bromination of 2-aminobenzamide was achieved using N-bromosuccinimide in chloroform-carbon tetrachloride mixture at room temperature for 3 h to afford 2-amino-3,5-dibromobenzamide in high yield and purity. 2-Amino-3,5-dibromobenzamide was, in turn, condensed with benzaldehyde derivatives in t...

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Bibliographic Details
Main Authors: M. J. Mphahlele, M. M. Maluleka, T. A. Khoza
Format: Article
Language:English
Published: Chemical Society of Ethiopia 2014-01-01
Series:Bulletin of the Chemical Society of Ethiopia
Subjects:
2
6
Online Access:http://www.ajol.info/index.php/bcse/article/view/100079