<i>N</i>-Heterocycles Scaffolds as <i>Quorum Sensing</i> Inhibitors. Design, Synthesis, Biological and Docking Studies

<i>N</i>-Heterocycles Scaffolds as <i>Quorum Sensing</i> Inhibitors. Design, Synthesis, Biological and Docking Studies

<i>Quorum sensing</i> is a communication system among bacteria to sense the proper time to express their virulence factors. <i>Quorum sensing</i> inhibition is a therapeutic strategy to block bacterial mechanisms of virulence. The aim of this study was to synthesize and evalu...

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Bibliographic Details
Main Authors: Alfredo Fuentes-Gutiérrez, Everardo Curiel-Quesada, José Correa-Basurto, Alberto Martínez-Muñoz, Alicia Reyes-Arellano
Format: Article
Language:English
Published: MDPI AG 2020-12-01
Series:International Journal of Molecular Sciences
Subjects:
heterocycles synthesis
new AHL bioisosteres
π–π interactions
<i>quorum sensing</i>
Online Access:https://www.mdpi.com/1422-0067/21/24/9512

Internet

https://www.mdpi.com/1422-0067/21/24/9512

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