An integrative computational analysis provides evidence for FBN1-associated network deregulation in trisomy 21

Summary Although approximately 50% of Down Syndrome (DS) patients have heart abnormalities, they exhibit an overprotection against cardiac abnormalities related with the connective tissue, for example a lower risk of coronary artery disease. A recent study reported a case of a person affected by DS...

Full description

Bibliographic Details
Main Authors: Mireia Vilardell, Sergi Civit, Ralf Herwig
Format: Article
Language:English
Published: The Company of Biologists 2013-06-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/2/8/771