Successful Direct Acting Antiviral Therapy in Chronic Hepatitis C Normalizes IFNγ and IL2 Production in T Cells Together with TLR8 Expression and Functionality in Peripheral Blood Mononuclear Cells

Successful Direct Acting Antiviral Therapy in Chronic Hepatitis C Normalizes IFNγ and IL2 Production in T Cells Together with TLR8 Expression and Functionality in Peripheral Blood Mononuclear Cells

Chronic hepatitis C infection (HCV) activates a systemic cell-mediated immune response characterized by the production of IFNγ and an innate immune response addressed by the activation of TLR signaling. We aimed to investigate whether HCV eradication by direct acting antivirals (DAA) leads to a reco...

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Bibliographic Details
Main Authors: María Teresa Arias-Loste, Joaquín Cabezas, Susana Llerena, Paula Iruzubieta, David San-Segundo, David Merino, Antonio Cuadrado, José Pedro Vaqué, Marcos López-Hoyos, Javier Crespo
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Viruses
Subjects:
chronic hepatitis C
toll-like receptors
direct acting antivirals
Online Access:https://www.mdpi.com/1999-4915/13/4/635

Internet

https://www.mdpi.com/1999-4915/13/4/635

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